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REVERSE TRANSCRIPTASE, HIV
Descriptors Found:
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DeCS
Descriptor
English
:
HIV Reverse Transcriptase
Descriptor
Spanish
:
Transcriptasa Inversa del VIH
Descriptor
Portuguese
:
Transcriptase Reversa do HIV
Synonyms
English
:
Reverse Transcriptase, HIV
Reverse Transcriptase, Human Immunodeficiency Virus
Transcriptase, HIV Reverse
Tree Number:
D08.811.913.696.445.308.300.750.187
D12.776.964.775.375.545.875
D12.776.964.775.375.750.187
D12.776.964.775.562.764.875
D12.776.964.970.600.850.375.545.875
D12.776.964.970.600.850.375.750.187
Definition
English
:
A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor protein. The heterodimer also includes an RNAse H activity (
RIBONUCLEASE H
, HUMAN IMMUNODEFICIENCY VIRUS) that plays an essential role the viral replication process.
History Note
English
:
2008
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52726
Unique Identifier:
D054303
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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